MLB · Wednesday, April 15
Guardians vs Cardinals Betting Odds – Wednesday, April 15
Last game: Wednesday, April 15, 2026 · 1:15 PM EDT · Busch Stadium, St. Louis, MO
Odds by Fanduel, updated Oct 10, 5:08 AM ET
MLB
Wednesday, April 15
1:15 PM EDT
@ Busch Stadium, St. Louis, MO
Final
- St. Louis Cardinals are favored by 1.5 runs at -1900
- Expected total is 8.5 runs, down from the opening 9.5
- Cardinals SP Hunter Dobbins is Out
Guardians vs Cardinals odds
Odds by Fanduel, updated Oct 10, 5:08 AM ETBet at Fanduel
How has the line moved?
| Captured | Cardinals spread | Total |
|---|---|---|
| Thu, Apr 9, 1:15 PM EDT | -1.5 | 9.5 |
| Sat, May 16, 6:50 AM EDT | -1.5 | 9.5 |
| Mon, Jun 22, 12:25 AM EDT | -1.5 | 9 |
| Tue, Jul 28, 6:01 PM EDT | -1.5 | 9 |
| Thu, Sep 3, 11:36 AM EDT | -1.5 | 8.5 |
| Sat, Oct 10, 5:11 AM EDT | -1.5 | 8.5 |
Cardinals spread
Total (over/under)
Guardians vs Cardinals team comparison
| Guardians | Cardinals | |
|---|---|---|
| 85-77 | Record | 77-85 |
| 4.2 | Runs per game | 4.4 |
| 4.1 | Opponent runs/game | 4.6 |
| +0.1 | Run differential | -0.2 |
| 0 | Head-to-head wins | 3 |
Injuries on both sides
| Team | Player | Pos | Status | Injury | Updated |
|---|---|---|---|---|---|
 Guardians | Rhys Hoskins | 1B | Injury reserve | Inflammation | Wed, Oct 7, 8:15 PM EDT |
| Guardians | Colin Holderman | RP | Injury reserve | Surgery | Wed, Oct 7, 8:15 PM EDT |
 Cardinals | Max Rajcic | RP | Injury reserve | Surgery | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Hunter Dobbins | SP | Out | Surgery | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Everson Pereira | RF | Injury reserve | Bruise | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Blaze Jordan | 3B | Injury reserve | Sprain | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Joshua Baez | LF | Injury reserve | Strain | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Masyn Winn | SS | Out | Soreness | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Richard Fitts | SP | Day-to-day | Surgery | Wed, Oct 7, 8:15 PM EDT |
Consensus Bets on this game
No consensus data yet for Guardians at Cardinals. Check back closer to game time.
Previous games
Frequently asked questions
Who is favoured in Guardians vs Cardinals?
St. Louis Cardinals were favoured by 1.5 runs (-1.5)
What is the spread for Guardians vs Cardinals?
Cardinals -1.5, Guardians +1.5. Opened at -1.5 for Cardinals
What time is Guardians vs Cardinals?
No game is currently scheduled
What is Guardians vs Cardinals head-to-head record?
Guardians 0, Cardinals 3 in recent games