MLB · Wednesday, April 22
White Sox vs Diamondbacks Betting Odds – Wednesday, April 22
Last game: Wednesday, April 22, 2026 · 9:40 PM EDT · Chase Field, Arizona, AZ
Odds by Fanduel, updated Oct 9, 5:19 AM ET
MLB
Wednesday, April 22
9:40 PM EDT
@ Chase Field, Arizona, AZ
Final
- Arizona Diamondbacks are favored by 1.5 runs at -1110
- Expected total is 8 runs, up from the opening 7.5
- White Sox RP Jordan Leasure is Injury reserve
White Sox vs Diamondbacks odds
Odds by Fanduel, updated Oct 9, 5:19 AM ETBet at Fanduel
How has the line moved?
| Captured | Diamondbacks spread | Total |
|---|---|---|
| Thu, Apr 16, 9:40 PM EDT | -1.5 | 7.5 |
| Thu, May 21, 11:12 PM EDT | -1.5 | 7.5 |
| Fri, Jun 26, 12:45 AM EDT | -1.5 | 7.5 |
| Fri, Jul 31, 2:18 AM EDT | -1.5 | 8 |
| Fri, Sep 4, 3:51 AM EDT | -1.5 | 8 |
| Fri, Oct 9, 5:24 AM EDT | -1.5 | 8 |
Diamondbacks spread
Total (over/under)
White Sox vs Diamondbacks team comparison
| White Sox | Diamondbacks | |
|---|---|---|
| 84-78 | Record | 86-76 |
| 4.8 | Runs per game | 4.6 |
| 4.4 | Opponent runs/game | 4.5 |
| +0.3 | Run differential | +0.1 |
| 0 | Head-to-head wins | 4 |
Injuries on both sides
| Team | Player | Pos | Status | Injury | Updated |
|---|---|---|---|---|---|
 White Sox | Jordan Leasure | RP | Injury reserve | Surgery | Wed, Oct 7, 8:15 PM EDT |
| White Sox | Mike Vasil | Starting Pitcher | Injury reserve | Surgery | Wed, Oct 7, 8:15 PM EDT |
| White Sox | Tanner Murray | 2B | Injury reserve | Surgery | Wed, Oct 7, 8:15 PM EDT |
| White Sox | Brooks Baldwin | Second Baseman | Injury reserve | Surgery | Wed, Oct 7, 8:15 PM EDT |
| White Sox | Joey Bart | C | Injury reserve | Fracture | Wed, Oct 7, 8:15 PM EDT |
| White Sox | Luis Castillo | SP | Injury reserve | Pinched Nerve | Wed, Oct 7, 8:15 PM EDT |
 Diamondbacks | Ryan Thompson | RP | Injury reserve | Strain | Wed, Oct 7, 8:15 PM EDT |
| Diamondbacks | Tyler Locklear | 1B | Injury reserve | Fracture | Wed, Oct 7, 8:15 PM EDT |
| Diamondbacks | Corbin Burnes | SP | Injury reserve | Inflammation | Wed, Oct 7, 8:15 PM EDT |
Consensus Bets on this game
No consensus data yet for White Sox at Diamondbacks. Check back closer to game time.
Previous games
| Date | Away | Home | Line | Total | Result | |
|---|---|---|---|---|---|---|
| Fri, Mar 6 | White Sox | Diamondbacks | -1.5 | 8.5 | Final | |
| Thu, Mar 19 | Diamondbacks | White Sox | +1.5 | 9 | Final | |
| Tue, Apr 21 | White Sox | Diamondbacks | -1.5 | 9 | Final | |
| Wed, Apr 22 | White Sox | Diamondbacks | -1.5 | 8 | Final |
Frequently asked questions
Who is favoured in White Sox vs Diamondbacks?
Arizona Diamondbacks were favoured by 1.5 runs (-1.5)
What is the spread for White Sox vs Diamondbacks?
Diamondbacks -1.5, White Sox +1.5. Opened at -1.5 for Diamondbacks
What time is White Sox vs Diamondbacks?
No game is currently scheduled
What is White Sox vs Diamondbacks head-to-head record?
White Sox 0, Diamondbacks 4 in recent games