NFL · Week 14
Rams vs 49ers Betting Odds – Week 14
Saturday, December 12, 2026 · 7:00 PM EST · San Francisco Arena, San Francisco, CA
Updated Oct 29, 6:36 AM ET
Week 14
Saturday, December 12
7:00 PM EST
@ San Francisco Arena, San Francisco, CA
- Los Angeles Rams visit San Francisco 49ers on Saturday, December 12 at 7:00 PM EST
- No Fanduel odds are posted yet for this game
- 49ers Fullback Kyle Juszczyk is Out
Rams vs 49ers team comparison
| Rams | 49ers | |
|---|---|---|
| 3-4 | Record | 6-1 |
| 24.3 | Points per game | 28.1 |
| 22.7 | Opponent points/game | 19.9 |
| +1.6 | Points differential | +8.3 |
| 0 | Head-to-head wins | 1 |
Injuries on both sides
| Team | Player | Pos | Status | Injury | Updated |
|---|---|---|---|---|---|
 Rams | Justin Dedich | Guard | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Rams | Eddie Walls III | Linebacker | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Rams | Matthew Caldwell | Quarterback | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Rams | Daniel Rickert | Defensive End | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Rams | Keir Thomas II | Linebacker | Injury reserve | ir | Wed, Oct 7, 8:15 PM EDT |
| Rams | Keagen Trost | Offensive Tackle | Injury reserve | Hamstring | Wed, Oct 7, 8:15 PM EDT |
| Rams | Tutu Atwell | Wide Receiver | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Rams | CJ Daniels | Wide Receiver | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Rams | Max Klare | Tight End | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Rams | Bill Murray | Guard | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Rams | Ty Simpson | Quarterback | Not playing | Back | Wed, Oct 7, 8:15 PM EDT |
| Rams | Davis Allen | Tight End | May play | Concussion | Wed, Oct 7, 8:15 PM EDT |
| Rams | Kam Curl | Safety | May play | Ankle | Wed, Oct 7, 8:15 PM EDT |
| Rams | Myles Garrett | Defensive End | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Rams | Nate Landman | Linebacker | May play | Shoulder | Wed, Oct 7, 8:15 PM EDT |
| Rams | Omar Speights | Linebacker | May play | Hip | Wed, Oct 7, 8:15 PM EDT |
| Rams | Kamren Kinchens | Safety | May play | Hamstring | Wed, Oct 7, 8:15 PM EDT |
| Rams | Puka Nacua | Wide Receiver | May play | Hip | Wed, Oct 7, 8:15 PM EDT |
| Rams | Jordan Whittington | Wide Receiver | May play | Quadriceps | Wed, Oct 7, 8:15 PM EDT |
| Rams | Ronnie Rivers | Running Back | Injury reserve | Calf | Wed, Oct 7, 8:15 PM EDT |
| Rams | Terrance Ferguson | Tight End | Injury reserve | Ankle | Wed, Oct 7, 8:15 PM EDT |
| Rams | Alaric Jackson | Offensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Rams | Colby Parkinson | Tight End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Rams | Maximus Pulley | Safety | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Rams | Jaylen Watson | Cornerback | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Rams | Aaron Donald | Defensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Rams | Josh Wallace | Cornerback | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Rams | Josaiah Stewart | Linebacker | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Rams | Cam Lampkin | Cornerback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Rams | Konata Mumpfield | Wide Receiver | May play | Rotator cuff | Wed, Oct 7, 8:15 PM EDT |
 49ers | Isaac Guerendo | Running Back | Out 4+ games | Pectoral | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Brandon Aiyuk | Wide Receiver | Reserve | Head | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Christian Kirk | Wide Receiver | Injury reserve | Calf | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Mykel Williams | Defensive End | Out 4+ games | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Ricky Pearsall | Wide Receiver | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Andrew Farmer II | Defensive End | Injury reserve | Back | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Darrick Forrest | Safety | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Mikail Kamara | Defensive End | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Sam Okuayinonu | Defensive Tackle | Injury reserve | Foot | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Brett Toth | Center | Injury reserve | Concussion | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Nate Hobbs | Cornerback | Injury reserve | ir | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Nick Martin | Linebacker | Injury reserve | Hamstring | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Austen Pleasants | Offensive Tackle | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Nick Zakelj | Offensive Tackle | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Alfred Collins | Defensive Tackle | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Tatum Bethune | Linebacker | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Enrique Cruz Jr. | Offensive Tackle | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jordan James | Running Back | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Ephesians Prysock | Cornerback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Kurtis Rourke | Quarterback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jordan Watkins | Wide Receiver | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| 49ers | De'Zhaun Stribling | Wide Receiver | Injury reserve | Ankle | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jake Tonges | Tight End | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Kyle Juszczyk | Fullback | Out | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Khalid Kareem | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| 49ers | George Kittle | Tight End | May play | Achilles | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Eddy Pineiro | Place Kicker | May play | Illness | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Keion White | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Kaelon Black | Running Back | May play | Illness | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Romello Height | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jack Jones | Cornerback | May play | Foot | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Demarcus Robinson | Wide Receiver | Injury reserve | Ankle | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Mike Evans | Wide Receiver | May play | Ribs | Wed, Oct 7, 8:15 PM EDT |
| 49ers | James Thompson Jr. | Defensive Tackle | Likely out | doubtful | Wed, Oct 7, 8:15 PM EDT |
| 49ers | C.J. West | Defensive Tackle | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Nick Bosa | Defensive End | Likely out | doubtful | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Dre Greenlaw | Linebacker | May play | Quadriceps | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Gracen Halton | Defensive Tackle | May play | Ankle | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Trent Williams | Offensive Tackle | May play | Neck | Wed, Oct 7, 8:15 PM EDT |
| 49ers | KhaDarel Hodge | Wide Receiver | May play | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jaden Dugger | Linebacker | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Marques Sigle | Safety | Out | out | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Upton Stout | Cornerback | May play | Shoulder | Wed, Oct 7, 8:15 PM EDT |
Consensus Bets on this game
No consensus data yet for Rams at 49ers. Check back closer to game time.
Previous games
Frequently asked questions
Who is favored in Rams vs 49ers on Saturday, December 12?
No line is posted yet
What is the spread for Rams vs 49ers on Saturday, December 12?
No spread is posted yet
What time is Rams vs 49ers on Saturday, December 12?
Saturday, December 12, 2026 at 7:00 PM EST, San Francisco Arena, San Francisco, CA
What is Rams vs 49ers head-to-head record?
Rams 0, 49ers 1 in recent games