NFL · Week 12
Packers vs Rams Betting Odds – Week 12
Wednesday, November 25, 2026 · 8:00 PM EST · SoFi Stadium, Los Angeles, CA
Odds by Fanduel, updated Oct 9, 4:23 AM ET
- Green Bay Packers are favored by 4 points at -597, Wednesday, November 25 at 8:00 PM EST
- Expected total is 44.5 points, down from the opening 45.5
- Packers Tight End Luke Musgrave is Out 4+ games
Packers vs Rams odds
Odds by Fanduel, updated Oct 9, 4:23 AM ETBet at Fanduel
How has the line moved?
| Captured | Rams spread | Total |
|---|---|---|
| Wed, Oct 7, 4:30 AM EDT | +4.5 | 45.5 |
| Wed, Oct 7, 2:06 PM EDT | +4.5 | 45.5 |
| Wed, Oct 7, 11:42 PM EDT | +4 | 45 |
| Thu, Oct 8, 9:18 AM EDT | +4 | 45 |
| Thu, Oct 8, 6:54 PM EDT | +4 | 44.5 |
| Fri, Oct 9, 4:30 AM EDT | +4 | 44.5 |
Rams spread
Total (over/under)
Packers vs Rams team comparison
| Packers | Rams | |
|---|---|---|
| 2-2 | Record | 2-2 |
| 18.3 | Points per game | 21.3 |
| 26.3 | Opponent points/game | 20.8 |
| -8.0 | Points differential | +0.5 |
| 0 | Head-to-head wins | 0 |
Injuries on both sides
| Team | Player | Pos | Status | Injury | Updated |
|---|---|---|---|---|---|
 Packers | Luke Musgrave | Tight End | Out 4+ games | Neck | Wed, Oct 7, 8:15 PM EDT |
| Packers | Micah Parsons | Defensive End | Out 4+ games | Knee | Wed, Oct 7, 8:15 PM EDT |
| Packers | Jordon Riley | Defensive Tackle | Out 4+ games | out | Wed, Oct 7, 8:15 PM EDT |
| Packers | Johnathan Baldwin II | Safety | Injury reserve | ir | Wed, Oct 7, 8:15 PM EDT |
| Packers | Marlon Jones | Cornerback | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Packers | Warren Brinson | Defensive Tackle | Injury reserve | Calf/groin | Wed, Oct 7, 8:15 PM EDT |
| Packers | Trey Dean III | Safety | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Packers | Collin Oliver | Defensive End | Injury reserve | Calf | Wed, Oct 7, 8:15 PM EDT |
| Packers | Savion Williams | Wide Receiver | Injury reserve | Ankle | Wed, Oct 7, 8:15 PM EDT |
| Packers | Thomas Yassmin | Tight End | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Packers | Aaron Banks | Guard | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Packers | Ty'Ron Hopper | Linebacker | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Packers | Anthony Campbell | Defensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Packers | Travis Glover | Offensive Tackle | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Packers | J. Michael Sturdivant | Wide Receiver | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Packers | Josh Whyle | Tight End | May play | Neck | Wed, Oct 7, 8:15 PM EDT |
| Packers | Brandon Cisse | Cornerback | May play | Concussion | Wed, Oct 7, 8:15 PM EDT |
| Packers | Zach Bako-Bewele | Offensive Tackle | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Packers | Javon Hargrave | Defensive Tackle | May play | Concussion/knee | Wed, Oct 7, 8:15 PM EDT |
| Packers | Barryn Sorrell | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Packers | Lukas Van Ness | Defensive End | May play | Shoulder | Wed, Oct 7, 8:15 PM EDT |
| Packers | Devonte Wyatt | Defensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Packers | Benjamin St-Juste | Cornerback | May play | out | Wed, Oct 7, 8:15 PM EDT |
| Packers | John Williams | Guard | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Packers | Jayden Reed | Wide Receiver | Injury reserve | Neck | Wed, Oct 7, 8:15 PM EDT |
| Packers | Donovan Jennings | Guard | May play | Hand | Wed, Oct 7, 8:15 PM EDT |
| Packers | Bo Melton | Wide Receiver | May play | Melton is questionable to retu… | Wed, Oct 7, 8:15 PM EDT |
| Packers | Edgerrin Cooper | Linebacker | Injury reserve | Achilles | Wed, Oct 7, 8:15 PM EDT |
| Packers | Anthony Belton | Offensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Packers | Jacob Monk | Center | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Packers | Karl Brooks | Defensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Packers | Jager Burton | Center | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Packers | Kevin Zeitler | Guard | Not playing | Zeitler is inactive for Week 4… | Wed, Oct 7, 8:15 PM EDT |
| Packers | Chris Brooks | Running Back | May play | Ankle | Wed, Oct 7, 8:15 PM EDT |
 Rams | Justin Dedich | Guard | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Rams | Eddie Walls III | Linebacker | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Rams | Matthew Caldwell | Quarterback | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Rams | Daniel Rickert | Defensive End | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Rams | Keir Thomas II | Linebacker | Injury reserve | ir | Wed, Oct 7, 8:15 PM EDT |
| Rams | Keagen Trost | Offensive Tackle | Injury reserve | Hamstring | Wed, Oct 7, 8:15 PM EDT |
| Rams | Tutu Atwell | Wide Receiver | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Rams | CJ Daniels | Wide Receiver | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Rams | Max Klare | Tight End | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Rams | Bill Murray | Guard | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Rams | Ty Simpson | Quarterback | Not playing | Back | Wed, Oct 7, 8:15 PM EDT |
| Rams | Davis Allen | Tight End | May play | Concussion | Wed, Oct 7, 8:15 PM EDT |
| Rams | Kam Curl | Safety | May play | Ankle | Wed, Oct 7, 8:15 PM EDT |
| Rams | Myles Garrett | Defensive End | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Rams | Nate Landman | Linebacker | May play | Shoulder | Wed, Oct 7, 8:15 PM EDT |
| Rams | Omar Speights | Linebacker | May play | Hip | Wed, Oct 7, 8:15 PM EDT |
| Rams | Kamren Kinchens | Safety | May play | Hamstring | Wed, Oct 7, 8:15 PM EDT |
| Rams | Puka Nacua | Wide Receiver | May play | Hip | Wed, Oct 7, 8:15 PM EDT |
| Rams | Jordan Whittington | Wide Receiver | May play | Quadriceps | Wed, Oct 7, 8:15 PM EDT |
| Rams | Ronnie Rivers | Running Back | Injury reserve | Calf | Wed, Oct 7, 8:15 PM EDT |
| Rams | Terrance Ferguson | Tight End | Injury reserve | Ankle | Wed, Oct 7, 8:15 PM EDT |
| Rams | Alaric Jackson | Offensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Rams | Colby Parkinson | Tight End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Rams | Maximus Pulley | Safety | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Rams | Jaylen Watson | Cornerback | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Rams | Aaron Donald | Defensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Rams | Josh Wallace | Cornerback | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Rams | Josaiah Stewart | Linebacker | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Rams | Cam Lampkin | Cornerback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Rams | Konata Mumpfield | Wide Receiver | May play | Rotator cuff | Wed, Oct 7, 8:15 PM EDT |
Consensus Bets on this game
No consensus data yet for Packers at Rams. Check back closer to game time.
Frequently asked questions
Who is favoured in Packers vs Rams on Wednesday, November 25?
Green Bay Packers are favoured by 4 points (-4)
What is the spread for Packers vs Rams on Wednesday, November 25?
Rams +4, Packers -4. Opened at +4.5 for Rams
What time is Packers vs Rams on Wednesday, November 25?
Wednesday, November 25, 2026 at 8:00 PM EST, SoFi Stadium, Los Angeles, CA
What is Packers vs Rams head-to-head record?
Packers 0, Rams 0 in recent games