NHL · Wednesday, October 21
Flyers vs Sabres Betting Odds – Wednesday, October 21
Wednesday, October 21, 2026 · 7:30 PM EDT · KeyBank Center, Buffalo, NY
Odds by Fanduel, updated Oct 9, 2:45 AM ET
- Philadelphia Flyers are favored by 1.5 goals at -583, Wednesday, October 21 at 7:30 PM EDT
- Expected total is 6.5 goals, up from the opening 5
- Sabres LW T. Placeholder is Out
Flyers vs Sabres odds
Odds by Fanduel, updated Oct 9, 2:45 AM ETBet at Fanduel
How has the line moved?
| Captured | Sabres spread | Total |
|---|---|---|
| Wed, Oct 7, 2:47 AM EDT | +1.5 | 5 |
| Wed, Oct 7, 12:23 PM EDT | +1.5 | 5.5 |
| Wed, Oct 7, 9:59 PM EDT | +1.5 | 5.5 |
| Thu, Oct 8, 7:35 AM EDT | +1.5 | 6 |
| Thu, Oct 8, 5:11 PM EDT | +1.5 | 6 |
| Fri, Oct 9, 2:47 AM EDT | +1.5 | 6.5 |
Sabres spread
Total (over/under)
Flyers vs Sabres team comparison
| Flyers | Sabres | |
|---|---|---|
| 0-2 | Record | 2-1 |
| 0-2 | Record | 2-1 |
| 0.000 | Win % | 0.667 |
| — | Home record | — |
| 0 | Head-to-head wins | 0 |
Injuries on both sides
| Team | Player | Pos | Status | Injury | Updated |
|---|---|---|---|---|---|
 Flyers | K. Example | D | May play | Hamstring | Thu, Oct 8, 3:47 AM EDT |
| Flyers | C. Placeholder | LW | May play | Calf | Thu, Oct 8, 2:47 PM EDT |
| Flyers | J. Preview | C | Injury reserve | Back | Fri, Oct 9, 12:47 AM EDT |
 Sabres | M. Test | LW | Day-to-day | Wrist | Thu, Oct 8, 4:47 PM EDT |
| Sabres | T. Placeholder | LW | Out | Calf | Thu, Oct 8, 9:47 AM EDT |
| Sabres | S. Placeholder | C | May play | Concussion | Fri, Oct 9, 2:47 AM EDT |
Consensus Bets on this game
No consensus data yet for Flyers at Sabres. Check back closer to game time.
Frequently asked questions
Who is favoured in Flyers vs Sabres on Wednesday, October 21?
Philadelphia Flyers are favoured by 1.5 goals (-1.5)
What is the spread for Flyers vs Sabres on Wednesday, October 21?
Sabres +1.5, Flyers -1.5. Opened at +1.5 for Sabres
What time is Flyers vs Sabres on Wednesday, October 21?
Wednesday, October 21, 2026 at 7:30 PM EDT, KeyBank Center, Buffalo, NY
What is Flyers vs Sabres head-to-head record?
Flyers 0, Sabres 0 in recent games