NFL · Week 7
49ers vs Falcons Betting Odds – Week 7
Sunday, October 25, 2026 · 1:00 PM EDT · Mercedes-Benz Stadium, Atlanta, GA
Odds by Fanduel, updated Oct 9, 5:22 AM ET
- Atlanta Falcons are favored by 5 points at -1762, Sunday, October 25 at 1:00 PM EDT
- Expected total is 45.5 points, up from the opening 45
- 49ers Fullback Kyle Juszczyk is Out
49ers vs Falcons odds
Odds by Fanduel, updated Oct 9, 5:22 AM ETBet at Fanduel
How has the line moved?
| Captured | Falcons spread | Total |
|---|---|---|
| Wed, Oct 7, 5:26 AM EDT | -5 | 45 |
| Wed, Oct 7, 3:02 PM EDT | -5 | 45.5 |
| Thu, Oct 8, 12:38 AM EDT | -5 | 45.5 |
| Thu, Oct 8, 10:14 AM EDT | -5 | 45.5 |
| Thu, Oct 8, 7:50 PM EDT | -5 | 45.5 |
| Fri, Oct 9, 5:26 AM EDT | -5 | 45.5 |
Falcons spread
Total (over/under)
49ers vs Falcons team comparison
| 49ers | Falcons | |
|---|---|---|
| 4-0 | Record | 2-2 |
| 30.5 | Points per game | 24.0 |
| 16.0 | Opponent points/game | 23.0 |
| +14.5 | Points differential | +1.0 |
| 0 | Head-to-head wins | 0 |
Injuries on both sides
| Team | Player | Pos | Status | Injury | Updated |
|---|---|---|---|---|---|
 49ers | Isaac Guerendo | Running Back | Out 4+ games | Pectoral | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Brandon Aiyuk | Wide Receiver | Reserve | Head | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Christian Kirk | Wide Receiver | Injury reserve | Calf | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Mykel Williams | Defensive End | Out 4+ games | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Ricky Pearsall | Wide Receiver | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Andrew Farmer II | Defensive End | Injury reserve | Back | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Darrick Forrest | Safety | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Mikail Kamara | Defensive End | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Sam Okuayinonu | Defensive Tackle | Injury reserve | Foot | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Brett Toth | Center | Injury reserve | Concussion | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Nate Hobbs | Cornerback | Injury reserve | ir | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Nick Martin | Linebacker | Injury reserve | Hamstring | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Austen Pleasants | Offensive Tackle | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Nick Zakelj | Offensive Tackle | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Alfred Collins | Defensive Tackle | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Tatum Bethune | Linebacker | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Enrique Cruz Jr. | Offensive Tackle | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jordan James | Running Back | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Ephesians Prysock | Cornerback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Kurtis Rourke | Quarterback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jordan Watkins | Wide Receiver | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| 49ers | De'Zhaun Stribling | Wide Receiver | Injury reserve | Ankle | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jake Tonges | Tight End | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Kyle Juszczyk | Fullback | Out | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Khalid Kareem | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| 49ers | George Kittle | Tight End | May play | Achilles | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Eddy Pineiro | Place Kicker | May play | Illness | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Keion White | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Kaelon Black | Running Back | May play | Illness | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Romello Height | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jack Jones | Cornerback | May play | Foot | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Demarcus Robinson | Wide Receiver | Injury reserve | Ankle | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Mike Evans | Wide Receiver | May play | Ribs | Wed, Oct 7, 8:15 PM EDT |
| 49ers | James Thompson Jr. | Defensive Tackle | Likely out | doubtful | Wed, Oct 7, 8:15 PM EDT |
| 49ers | C.J. West | Defensive Tackle | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Nick Bosa | Defensive End | Likely out | doubtful | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Dre Greenlaw | Linebacker | May play | Quadriceps | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Gracen Halton | Defensive Tackle | May play | Ankle | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Trent Williams | Offensive Tackle | May play | Neck | Wed, Oct 7, 8:15 PM EDT |
| 49ers | KhaDarel Hodge | Wide Receiver | May play | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jaden Dugger | Linebacker | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Marques Sigle | Safety | Out | out | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Upton Stout | Cornerback | May play | Shoulder | Wed, Oct 7, 8:15 PM EDT |
 Falcons | Michael Penix Jr. | Quarterback | May play | Knee | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Billy Bowman Jr. | Cornerback | May play | Achilles | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Storm Norton | Offensive Tackle | Out 4+ games | out | Wed, Oct 7, 8:15 PM EDT |
| Falcons | DeAngelo Malone | Linebacker | Out 4+ games | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Anterio Thompson | Defensive Tackle | Out 4+ games | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Jalon Walker | Linebacker | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Falcons | James Pearce Jr. | Linebacker | Suspended | reserve-sus | Wed, Oct 7, 8:15 PM EDT |
| Falcons | JD Bertrand | Linebacker | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Beaux Collins | Wide Receiver | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Trey Sermon | Running Back | Injury reserve | ir | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Tua Tagovailoa | Quarterback | May play | Ankle | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Cameron Williams | Offensive Lineman | Injury reserve | Ankle | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Malcolm DeWalt IV | Cornerback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Christian Harris | Linebacker | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Ethan Onianwa | Offensive Tackle | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Da'Shawn Hand | Defensive Tackle | Injury reserve | Quadriceps | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Chris Lindstrom | Guard | May play | Concussion | Wed, Oct 7, 8:15 PM EDT |
| Falcons | A.J. Terrell Jr. | Cornerback | Injury reserve | Groin | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Kendal Daniels | Linebacker | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Jawaan Taylor | Offensive Tackle | May play | Ribs | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Divine Deablo | Linebacker | May play | Hamstring | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Samson Ebukam | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Brandon Dorlus | Defensive Tackle | May play | Thumb | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Nick Muse | Tight End | May play | Shoulder | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Brian Robinson Jr. | Running Back | May play | Ankle | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Robert Longerbeam | Cornerback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Cooper Rush | Quarterback | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Jack Strand | Quarterback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Yasir Abdullah | Linebacker | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Jared Ivey | Linebacker | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Za'Darius Smith | Defensive End | May play | Concussion | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Jake Matthews | Offensive Tackle | May play | Groin | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Michael Jerrell | Offensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Falcons | Cameron Thomas | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
Consensus Bets on this game
No consensus data yet for 49ers at Falcons. Check back closer to game time.
Frequently asked questions
Who is favoured in 49ers vs Falcons on Sunday, October 25?
Atlanta Falcons are favoured by 5 points (-5)
What is the spread for 49ers vs Falcons on Sunday, October 25?
Falcons -5, 49ers +5. Opened at -5 for Falcons
What time is 49ers vs Falcons on Sunday, October 25?
Sunday, October 25, 2026 at 1:00 PM EDT, Mercedes-Benz Stadium, Atlanta, GA
What is 49ers vs Falcons head-to-head record?
49ers 0, Falcons 0 in recent games