NFL · Week 11
Vikings vs 49ers Betting Odds – Week 11
Sunday, November 22, 2026 · 8:20 PM EST · Estadio Banorte, San Francisco, CA
Odds by Fanduel, updated Oct 9, 7:18 AM ET
Week 11
Sunday, November 22
8:20 PM EST
@ Estadio Banorte, San Francisco, CA
- Minnesota Vikings are favored by 3 points at -350, Sunday, November 22 at 8:20 PM EST
- Expected total is 45.5 points, up from the opening 44
- 49ers Fullback Kyle Juszczyk is Out
Vikings vs 49ers odds
Odds by Fanduel, updated Oct 9, 7:18 AM ETBet at Fanduel
How has the line moved?
| Captured | 49ers spread | Total |
|---|---|---|
| Wed, Oct 7, 7:22 AM EDT | +2.5 | 44 |
| Wed, Oct 7, 4:58 PM EDT | +2.5 | 44 |
| Thu, Oct 8, 2:34 AM EDT | +3 | 45 |
| Thu, Oct 8, 12:10 PM EDT | +3 | 45 |
| Thu, Oct 8, 9:46 PM EDT | +3 | 45 |
| Fri, Oct 9, 7:22 AM EDT | +3 | 45.5 |
49ers spread
Total (over/under)
Vikings vs 49ers team comparison
| Vikings | 49ers | |
|---|---|---|
| 4-0 | Record | 4-0 |
| 21.5 | Points per game | 30.5 |
| 12.8 | Opponent points/game | 16.0 |
| +8.8 | Points differential | +14.5 |
| 0 | Head-to-head wins | 0 |
Injuries on both sides
| Team | Player | Pos | Status | Injury | Updated |
|---|---|---|---|---|---|
 Vikings | Jamal Adams | Linebacker | Injury reserve | ir | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Tyler Batty | Linebacker | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Tyreek Chappell | Cornerback | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Jeshaun Jones | Wide Receiver | Suspended | The NFL suspended Jones three … | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Michael Jurgens | Center | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Taki Taimani | Defensive Tackle | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Ben Yurosek | Tight End | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Audric Estime | Running Back | Injury reserve | Thigh | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Demond Claiborne | Running Back | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Nick Samac | Center | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Jakobe Thomas | Safety | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Caleb Tiernan | Offensive Tackle | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Zemaiah Vaughn | Cornerback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Elijah Williams | Defensive End | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Kyler Murray | Quarterback | Not playing | Concussion | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Jordan Mason | Running Back | Injury reserve | ir | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Blake Cashman | Linebacker | May play | Elbow | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Brian O'Neill | Offensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Andrew Van Ginkel | Linebacker | May play | Chest | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Jauan Jennings | Wide Receiver | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Tyrion Ingram-Dawkins | Defensive End | May play | Hip | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Brett Thorson | Punter | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Aaron Jones Sr. | Running Back | May play | Knee | Wed, Oct 7, 8:15 PM EDT |
| Vikings | DeeJay Dallas | Running Back | May play | Toe | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Jake Golday | Linebacker | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Jalen Redmond | Defensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Ivan Pace Jr. | Linebacker | May play | Personal | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Tavierre Thomas | Safety | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Justin Jefferson | Wide Receiver | May play | Ankle | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Charles Demmings | Cornerback | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Josh Oliver | Tight End | Injury reserve | Biceps | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Max Brosmer | Quarterback | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Donovan Jackson | Guard | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Christian Darrisaw | Offensive Tackle | May play | Concussion | Wed, Oct 7, 8:15 PM EDT |
| Vikings | Jordan Addison | Wide Receiver | May play | Hamstring | Wed, Oct 7, 8:15 PM EDT |
 49ers | Isaac Guerendo | Running Back | Out 4+ games | Pectoral | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Brandon Aiyuk | Wide Receiver | Reserve | Head | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Christian Kirk | Wide Receiver | Injury reserve | Calf | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Mykel Williams | Defensive End | Out 4+ games | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Ricky Pearsall | Wide Receiver | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Andrew Farmer II | Defensive End | Injury reserve | Back | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Darrick Forrest | Safety | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Mikail Kamara | Defensive End | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Sam Okuayinonu | Defensive Tackle | Injury reserve | Foot | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Brett Toth | Center | Injury reserve | Concussion | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Nate Hobbs | Cornerback | Injury reserve | ir | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Nick Martin | Linebacker | Injury reserve | Hamstring | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Austen Pleasants | Offensive Tackle | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Nick Zakelj | Offensive Tackle | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Alfred Collins | Defensive Tackle | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Tatum Bethune | Linebacker | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Enrique Cruz Jr. | Offensive Tackle | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jordan James | Running Back | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Ephesians Prysock | Cornerback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Kurtis Rourke | Quarterback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jordan Watkins | Wide Receiver | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| 49ers | De'Zhaun Stribling | Wide Receiver | Injury reserve | Ankle | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jake Tonges | Tight End | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Kyle Juszczyk | Fullback | Out | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Khalid Kareem | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| 49ers | George Kittle | Tight End | May play | Achilles | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Eddy Pineiro | Place Kicker | May play | Illness | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Keion White | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Kaelon Black | Running Back | May play | Illness | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Romello Height | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jack Jones | Cornerback | May play | Foot | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Demarcus Robinson | Wide Receiver | Injury reserve | Ankle | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Mike Evans | Wide Receiver | May play | Ribs | Wed, Oct 7, 8:15 PM EDT |
| 49ers | James Thompson Jr. | Defensive Tackle | Likely out | doubtful | Wed, Oct 7, 8:15 PM EDT |
| 49ers | C.J. West | Defensive Tackle | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Nick Bosa | Defensive End | Likely out | doubtful | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Dre Greenlaw | Linebacker | May play | Quadriceps | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Gracen Halton | Defensive Tackle | May play | Ankle | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Trent Williams | Offensive Tackle | May play | Neck | Wed, Oct 7, 8:15 PM EDT |
| 49ers | KhaDarel Hodge | Wide Receiver | May play | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jaden Dugger | Linebacker | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Marques Sigle | Safety | Out | out | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Upton Stout | Cornerback | May play | Shoulder | Wed, Oct 7, 8:15 PM EDT |
Consensus Bets on this game
No consensus data yet for Vikings at 49ers. Check back closer to game time.
Frequently asked questions
Who is favoured in Vikings vs 49ers on Sunday, November 22?
Minnesota Vikings are favoured by 3 points (-3)
What is the spread for Vikings vs 49ers on Sunday, November 22?
49ers +3, Vikings -3. Opened at +2.5 for 49ers
What time is Vikings vs 49ers on Sunday, November 22?
Sunday, November 22, 2026 at 8:20 PM EST, Estadio Banorte, San Francisco, CA
What is Vikings vs 49ers head-to-head record?
Vikings 0, 49ers 0 in recent games