NFL · Week 6
Titans vs Colts Betting Odds – Week 6
Sunday, October 18, 2026 · 1:00 PM EDT · Lucas Oil Stadium, Indianapolis, IN
Odds by Fanduel, updated Oct 9, 7:15 AM ET
- Indianapolis Colts are favored by 5 points at -1347, Sunday, October 18 at 1:00 PM EDT
- Expected total is 48 points, unchanged from the opening 48
- Colts Defensive End Arden Key is Out
Titans vs Colts odds
Odds by Fanduel, updated Oct 9, 7:15 AM ETBet at Fanduel
How has the line moved?
| Captured | Colts spread | Total |
|---|---|---|
| Wed, Oct 7, 7:21 AM EDT | -4.5 | 48 |
| Wed, Oct 7, 4:57 PM EDT | -4.5 | 48 |
| Thu, Oct 8, 2:33 AM EDT | -5 | 48 |
| Thu, Oct 8, 12:09 PM EDT | -5 | 48 |
| Thu, Oct 8, 9:45 PM EDT | -5 | 48 |
| Fri, Oct 9, 7:21 AM EDT | -5 | 48 |
Colts spread
Total (over/under)
Titans vs Colts team comparison
| Titans | Colts | |
|---|---|---|
| 0-4 | Record | 2-2 |
| 13.8 | Points per game | 25.5 |
| 20.8 | Opponent points/game | 26.0 |
| -7.0 | Points differential | -0.5 |
| 0 | Head-to-head wins | 0 |
Injuries on both sides
| Team | Player | Pos | Status | Injury | Updated |
|---|---|---|---|---|---|
 Titans | Jaylen Harrell | Linebacker | Injury reserve | ir | Wed, Oct 7, 8:15 PM EDT |
| Titans | Jaren Kanak | Tight End | Injury reserve | ir | Wed, Oct 7, 8:15 PM EDT |
| Titans | Kendell Brooks | Safety | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Titans | Milo Eifler | Linebacker | Injury reserve | ir | Wed, Oct 7, 8:15 PM EDT |
| Titans | Tanoh Kpassagnon | Defensive End | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Titans | Dorian Mausi | Linebacker | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Titans | Joshua Williams | Cornerback | Injury reserve | Pectoral | Wed, Oct 7, 8:15 PM EDT |
| Titans | Cedric Gray | Linebacker | May play | Concussion | Wed, Oct 7, 8:15 PM EDT |
| Titans | Brandon Crenshaw-Dickson | Offensive Tackle | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Titans | Atonio Mafi | Guard | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Titans | Jackie Marshall | Defensive Tackle | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Titans | Owen Pappoe | Linebacker | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Titans | Nicholas Singleton | Running Back | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Titans | James Williams Sr. | Linebacker | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Titans | Cor'Dale Flott | Cornerback | May play | Quadriceps | Wed, Oct 7, 8:15 PM EDT |
| Titans | Kylen Granson | Tight End | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Titans | Fernando Carmona | Guard | Injury reserve | Ankle | Wed, Oct 7, 8:15 PM EDT |
| Titans | Tony Pollard | Running Back | May play | Foot | Wed, Oct 7, 8:15 PM EDT |
| Titans | Tyjae Spears | Running Back | May play | Ankle | Wed, Oct 7, 8:15 PM EDT |
| Titans | Solomon Thomas | Defensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Titans | Daniel Bellinger | Tight End | May play | Illness | Wed, Oct 7, 8:15 PM EDT |
| Titans | Micah Robinson | Cornerback | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Titans | Michael Carter | Running Back | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Titans | Jaylon Jones | Cornerback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Titans | Jackson Slater | Guard | Injury reserve | Foot | Wed, Oct 7, 8:15 PM EDT |
| Titans | John Franklin-Myers | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Titans | Kevin Winston Jr. | Safety | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Titans | Garrett Dellinger | Guard | May play | Illness | Wed, Oct 7, 8:15 PM EDT |
| Titans | Drew Moss | Guard | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Titans | Amani Hooker | Safety | May play | Concussion | Wed, Oct 7, 8:15 PM EDT |
| Titans | Marcus Harris | Cornerback | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Titans | Jeffery Simmons | Defensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
 Colts | Cameron Mitchell | Cornerback | Injury reserve | ir | Wed, Oct 7, 8:15 PM EDT |
| Colts | Cam Taylor-Britt | Cornerback | Suspended | reserve-sus | Wed, Oct 7, 8:15 PM EDT |
| Colts | Will Mallory | Tight End | Injury reserve | Thumb | Wed, Oct 7, 8:15 PM EDT |
| Colts | D.J. Montgomery | Wide Receiver | Injury reserve | Abdomen | Wed, Oct 7, 8:15 PM EDT |
| Colts | Carson Towt | Tight End | Injury reserve | ir | Wed, Oct 7, 8:15 PM EDT |
| Colts | Austin Ajiake | Linebacker | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Colts | Johnathan Edwards | Cornerback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Colts | DJ Giddens | Running Back | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Colts | George Gumbs Jr. | Linebacker | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Colts | Riley Leonard | Quarterback | Not playing | Back | Wed, Oct 7, 8:15 PM EDT |
| Colts | Dalton Tucker | Guard | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Colts | Alec Pierce | Wide Receiver | Injury reserve | Head | Wed, Oct 7, 8:15 PM EDT |
| Colts | Ashton Dulin | Wide Receiver | May play | Hamstring | Wed, Oct 7, 8:15 PM EDT |
| Colts | Anthony Richardson Sr. | Quarterback | May play | Groin | Wed, Oct 7, 8:15 PM EDT |
| Colts | Micheal Clemons | Defensive End | Injury reserve | Toe | Wed, Oct 7, 8:15 PM EDT |
| Colts | Charvarius Ward | Cornerback | May play | Groin | Wed, Oct 7, 8:15 PM EDT |
| Colts | Darius Slayton | Wide Receiver | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Colts | Laiatu Latu | Defensive End | May play | Latu is questionable to return… | Wed, Oct 7, 8:15 PM EDT |
| Colts | Mo Alie-Cox | Tight End | May play | Illness | Wed, Oct 7, 8:15 PM EDT |
| Colts | Akeem Davis-Gaither | Linebacker | May play | Knee | Wed, Oct 7, 8:15 PM EDT |
| Colts | Keenan Allen | Wide Receiver | May play | Groin | Wed, Oct 7, 8:15 PM EDT |
| Colts | Arden Key | Defensive End | Out | Hamstring | Wed, Oct 7, 8:15 PM EDT |
| Colts | Jaylon Carlies | Linebacker | May play | Ribs | Wed, Oct 7, 8:15 PM EDT |
| Colts | Tanor Bortolini | Center | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
Consensus Bets on this game
No consensus data yet for Titans at Colts. Check back closer to game time.
Frequently asked questions
Who is favoured in Titans vs Colts on Sunday, October 18?
Indianapolis Colts are favoured by 5 points (-5)
What is the spread for Titans vs Colts on Sunday, October 18?
Colts -5, Titans +5. Opened at -4.5 for Colts
What time is Titans vs Colts on Sunday, October 18?
Sunday, October 18, 2026 at 1:00 PM EDT, Lucas Oil Stadium, Indianapolis, IN
What is Titans vs Colts head-to-head record?
Titans 0, Colts 0 in recent games