NFL · Week 13
49ers vs Giants Betting Odds – Week 13
Sunday, December 6, 2026 · 1:00 PM EST · MetLife Stadium, New York, NJ
Odds by Fanduel, updated Oct 9, 1:38 AM ET
- New York Giants are favored by 1 points at -142, Sunday, December 6 at 1:00 PM EST
- Expected total is 47.5 points, down from the opening 48.5
- 49ers Fullback Kyle Juszczyk is Out
49ers vs Giants odds
Odds by Fanduel, updated Oct 9, 1:38 AM ETBet at Fanduel
How has the line moved?
| Captured | Giants spread | Total |
|---|---|---|
| Wed, Oct 7, 1:38 AM EDT | -1.5 | 48.5 |
| Wed, Oct 7, 11:14 AM EDT | -1 | 48.5 |
| Wed, Oct 7, 8:50 PM EDT | -1 | 48 |
| Thu, Oct 8, 6:26 AM EDT | -1 | 48 |
| Thu, Oct 8, 4:02 PM EDT | -1 | 47.5 |
| Fri, Oct 9, 1:38 AM EDT | -1 | 47.5 |
Giants spread
Total (over/under)
49ers vs Giants team comparison
| 49ers | Giants | |
|---|---|---|
| 4-0 | Record | 3-1 |
| 30.5 | Points per game | 20.5 |
| 16.0 | Opponent points/game | 19.8 |
| +14.5 | Points differential | +0.8 |
| 0 | Head-to-head wins | 0 |
Injuries on both sides
| Team | Player | Pos | Status | Injury | Updated |
|---|---|---|---|---|---|
 49ers | Isaac Guerendo | Running Back | Out 4+ games | Pectoral | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Brandon Aiyuk | Wide Receiver | Reserve | Head | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Christian Kirk | Wide Receiver | Injury reserve | Calf | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Mykel Williams | Defensive End | Out 4+ games | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Ricky Pearsall | Wide Receiver | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Andrew Farmer II | Defensive End | Injury reserve | Back | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Darrick Forrest | Safety | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Mikail Kamara | Defensive End | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Sam Okuayinonu | Defensive Tackle | Injury reserve | Foot | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Brett Toth | Center | Injury reserve | Concussion | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Nate Hobbs | Cornerback | Injury reserve | ir | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Nick Martin | Linebacker | Injury reserve | Hamstring | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Austen Pleasants | Offensive Tackle | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Nick Zakelj | Offensive Tackle | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Alfred Collins | Defensive Tackle | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Tatum Bethune | Linebacker | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Enrique Cruz Jr. | Offensive Tackle | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jordan James | Running Back | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Ephesians Prysock | Cornerback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Kurtis Rourke | Quarterback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jordan Watkins | Wide Receiver | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| 49ers | De'Zhaun Stribling | Wide Receiver | Injury reserve | Ankle | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jake Tonges | Tight End | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Kyle Juszczyk | Fullback | Out | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Khalid Kareem | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| 49ers | George Kittle | Tight End | May play | Achilles | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Eddy Pineiro | Place Kicker | May play | Illness | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Keion White | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Kaelon Black | Running Back | May play | Illness | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Romello Height | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jack Jones | Cornerback | May play | Foot | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Demarcus Robinson | Wide Receiver | Injury reserve | Ankle | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Mike Evans | Wide Receiver | May play | Ribs | Wed, Oct 7, 8:15 PM EDT |
| 49ers | James Thompson Jr. | Defensive Tackle | Likely out | doubtful | Wed, Oct 7, 8:15 PM EDT |
| 49ers | C.J. West | Defensive Tackle | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Nick Bosa | Defensive End | Likely out | doubtful | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Dre Greenlaw | Linebacker | May play | Quadriceps | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Gracen Halton | Defensive Tackle | May play | Ankle | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Trent Williams | Offensive Tackle | May play | Neck | Wed, Oct 7, 8:15 PM EDT |
| 49ers | KhaDarel Hodge | Wide Receiver | May play | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jaden Dugger | Linebacker | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Marques Sigle | Safety | Out | out | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Upton Stout | Cornerback | May play | Shoulder | Wed, Oct 7, 8:15 PM EDT |
 Giants | Gunner Olszewski | Wide Receiver | Injury reserve | Achilles | Wed, Oct 7, 8:15 PM EDT |
| Giants | Roy Robertson-Harris | Defensive Tackle | Injury reserve | ir | Wed, Oct 7, 8:15 PM EDT |
| Giants | Rico Payton | Cornerback | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Giants | Jarrick Bernard-Converse | Cornerback | Injury reserve | ir | Wed, Oct 7, 8:15 PM EDT |
| Giants | Thaddeus Dixon | Cornerback | Injury reserve | Achilles | Wed, Oct 7, 8:15 PM EDT |
| Giants | Kendrick Green | Center | Injury reserve | ir | Wed, Oct 7, 8:15 PM EDT |
| Giants | Calvin Austin III | Wide Receiver | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Giants | Korie Black | Cornerback | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Giants | J.J. McCarthy | Quarterback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Giants | Dalen Cambre | Wide Receiver | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Giants | J.C. Davis | Offensive Tackle | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Giants | Thomas Fidone II | Tight End | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Giants | Najee Harris | Running Back | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Giants | Bobby Jamison-Travis | Defensive Tackle | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Giants | Nic Jones | Cornerback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Giants | Jason Pinnock | Safety | May play | Concussion | Wed, Oct 7, 8:15 PM EDT |
| Giants | Tyrone Tracy Jr. | Running Back | May play | Knee | Wed, Oct 7, 8:15 PM EDT |
| Giants | Paulson Adebo | Cornerback | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Giants | Deonte Banks | Cornerback | May play | Calf | Wed, Oct 7, 8:15 PM EDT |
| Giants | Chauncey Golston | Defensive End | May play | Neck | Wed, Oct 7, 8:15 PM EDT |
| Giants | Francis Mauigoa | Offensive Tackle | May play | Shoulder | Wed, Oct 7, 8:15 PM EDT |
| Giants | Micah McFadden | Linebacker | May play | Neck | Wed, Oct 7, 8:15 PM EDT |
| Giants | Greg Newsome II | Cornerback | May play | Ribs | Wed, Oct 7, 8:15 PM EDT |
| Giants | Andrew Thomas | Offensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Giants | Darius Alexander | Defensive Tackle | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Giants | Jaxson Dart | Quarterback | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Giants | Brian Burns | Linebacker | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Giants | Malik Nabers | Wide Receiver | May play | Knee | Wed, Oct 7, 8:15 PM EDT |
| Giants | Shelby Harris | Defensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Giants | Tyler Nubin | Safety | May play | Calf | Wed, Oct 7, 8:15 PM EDT |
| Giants | Devin Singletary | Running Back | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Giants | Josh Tupou | Defensive Tackle | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Giants | Nikko Reed | Cornerback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Giants | Jihad Ward | Linebacker | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Giants | Ar'Darius Washington | Safety | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Giants | Braxton Berrios | Wide Receiver | Injury reserve | Foot | Wed, Oct 7, 8:15 PM EDT |
| Giants | Isaiah Likely | Tight End | May play | Knee/groin | Wed, Oct 7, 8:15 PM EDT |
| Giants | Cam Skattebo | Running Back | May play | Shoulder | Wed, Oct 7, 8:15 PM EDT |
| Giants | Chris Manhertz | Tight End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
Consensus Bets on this game
No consensus data yet for 49ers at Giants. Check back closer to game time.
Frequently asked questions
Who is favoured in 49ers vs Giants on Sunday, December 6?
New York Giants are favoured by 1 points (-1)
What is the spread for 49ers vs Giants on Sunday, December 6?
Giants -1, 49ers +1. Opened at -1.5 for Giants
What time is 49ers vs Giants on Sunday, December 6?
Sunday, December 6, 2026 at 1:00 PM EST, MetLife Stadium, New York, NJ
What is 49ers vs Giants head-to-head record?
49ers 0, Giants 0 in recent games