NFL · Week 12
Commanders vs Cardinals Betting Odds – Week 12
Sunday, November 29, 2026 · 4:25 PM EST · State Farm Stadium, Arizona, AZ
Odds by Fanduel, updated Oct 9, 2:30 AM ET
Week 12
Sunday, November 29
4:25 PM EST
@ State Farm Stadium, Arizona, AZ
- Washington Commanders are favored by 2.5 points at -266, Sunday, November 29 at 4:25 PM EST
- Expected total is 46.5 points, down from the opening 47
- Commanders Defensive End Deatrich Wise Jr. is Out 4+ games
Commanders vs Cardinals odds
Odds by Fanduel, updated Oct 9, 2:30 AM ETBet at Fanduel
How has the line moved?
| Captured | Cardinals spread | Total |
|---|---|---|
| Wed, Oct 7, 2:33 AM EDT | +2 | 47 |
| Wed, Oct 7, 12:09 PM EDT | +2 | 46.5 |
| Wed, Oct 7, 9:45 PM EDT | +2.5 | 47 |
| Thu, Oct 8, 7:21 AM EDT | +2.5 | 46.5 |
| Thu, Oct 8, 4:57 PM EDT | +2 | 46.5 |
| Fri, Oct 9, 2:33 AM EDT | +2.5 | 46.5 |
Cardinals spread
Total (over/under)
Commanders vs Cardinals team comparison
| Commanders | Cardinals | |
|---|---|---|
| 1-3 | Record | 1-3 |
| 22.0 | Points per game | 21.8 |
| 30.5 | Opponent points/game | 29.3 |
| -8.5 | Points differential | -7.5 |
| 0 | Head-to-head wins | 0 |
Injuries on both sides
| Team | Player | Pos | Status | Injury | Updated |
|---|---|---|---|---|---|
 Commanders | Deatrich Wise Jr. | Defensive End | Out 4+ games | Quadriceps | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Trey Amos | Cornerback | Injury reserve | Ankle | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Jeremy McNichols | Running Back | Injury reserve | Quadriceps | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Laremy Tunsil | Offensive Tackle | Injury reserve | Triceps | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Dorance Armstrong | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Jer'Zhan Newton | Defensive Tackle | Injury reserve | Pectoral | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Ricky Barber | Defensive Tackle | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Treylon Burks | Wide Receiver | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Athan Kaliakmanis | Quarterback | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Luke McCaffrey | Wide Receiver | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Tanoa Togiai | Guard | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Frankie Luvu | Linebacker | May play | Groin | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Chig Okonkwo | Tight End | May play | Hamstring | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Jordan Magee | Linebacker | Injury reserve | Hamstring | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Tyler Owens | Safety | May play | Hamstring | Wed, Oct 7, 8:15 PM EDT |
| Commanders | K'Lavon Chaisson | Linebacker | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Jaylin Lane | Wide Receiver | Injury reserve | Ankle | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Charles Omenihu | Defensive End | May play | Groin | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Odafe Oweh | Linebacker | May play | Calf | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Daron Payne | Defensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Javon Kinlaw | Defensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Isaac Yiadom | Cornerback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Jayden Daniels | Quarterback | May play | Elbow | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Brandon Coleman | Guard | May play | Finger | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Sam Cosmi | Guard | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Nick Cross | Safety | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Kaytron Allen | Running Back | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Percy Butler | Safety | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Leo Chenal | Linebacker | Injury reserve | Neck | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Jeremy Reaves | Safety | May play | Finger | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Javontae Jean-Baptiste | Linebacker | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Rachaad White | Running Back | May play | Shoulder | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Nick Allegretti | Guard | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Lucas Patrick | Guard | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Amik Robertson | Cornerback | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Ben Sinnott | Tight End | May play | Ribs | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Terry McLaurin | Wide Receiver | May play | Hamstring | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Marcus Mariota | Quarterback | Likely out | Knee | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Stefon Diggs | Wide Receiver | May play | Hamstring | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Jacory Croskey-Merritt | Running Back | May play | Groin | Wed, Oct 7, 8:15 PM EDT |
| Commanders | Sonny Styles | Linebacker | May play | Groin | Wed, Oct 7, 8:15 PM EDT |
 Cardinals | James Conner | Running Back | Injury reserve | Foot | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Tip Reiman | Tight End | Out 4+ games | Ankle | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Joey Blount | Safety | Injury reserve | Neck | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Zachary Carter | Defensive Tackle | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Kaleb Proctor | Defensive Tackle | Injury reserve | ir | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Chase Bisontis | Guard | Injury reserve | ir | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Trey Benson | Running Back | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Jameson Geers | Tight End | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Dadrion Taylor-Demerson | Safety | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Isaiah Adams | Guard | May play | Ankle | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Garrett Williams | Cornerback | May play | Achilles | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Carson Beck | Quarterback | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Andrew Billings | Defensive Tackle | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Reggie Virgil | Wide Receiver | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Kitan Crawford | Safety | Injury reserve | Ankle | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Jack Gibbens | Linebacker | May play | Shoulder | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Roy Lopez | Defensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Max Melton | Cornerback | May play | Toe | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Isaac Seumalo | Guard | May play | Shoulder | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Cody Simon | Linebacker | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Josh Fryar | Offensive Tackle | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Will Johnson | Cornerback | Injury reserve | Neck | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Hjalte Froholdt | Center | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Walter Nolen III | Defensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Mack Wilson Sr. | Linebacker | May play | Thumb | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Josh Sweat | Linebacker | May play | Groin | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Cameron Robertson | Linebacker | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Starling Thomas V | Cornerback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Andrew Wingard | Safety | May play | Knee | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Hunter Long | Tight End | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Paris Johnson Jr. | Offensive Tackle | Injury reserve | Biceps | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Jeremiyah Love | Running Back | May play | Ankle | Wed, Oct 7, 8:15 PM EDT |
Consensus Bets on this game
No consensus data yet for Commanders at Cardinals. Check back closer to game time.
Frequently asked questions
Who is favoured in Commanders vs Cardinals on Sunday, November 29?
Washington Commanders are favoured by 2.5 points (-2.5)
What is the spread for Commanders vs Cardinals on Sunday, November 29?
Cardinals +2.5, Commanders -2.5. Opened at +2 for Cardinals
What time is Commanders vs Cardinals on Sunday, November 29?
Sunday, November 29, 2026 at 4:25 PM EST, State Farm Stadium, Arizona, AZ
What is Commanders vs Cardinals head-to-head record?
Commanders 0, Cardinals 0 in recent games