NFL · Week 17
Eagles vs 49ers Betting Odds – Week 17
Sunday, January 3, 2027 · 8:20 PM EST · Levi's Stadium, San Francisco, CA
Odds by Fanduel, updated Oct 9, 1:33 AM ET
- San Francisco 49ers are favored by 2.5 points at -283, Sunday, January 3 at 8:20 PM EST
- Expected total is 44 points, down from the opening 44.5
- 49ers Fullback Kyle Juszczyk is Out
Eagles vs 49ers odds
Odds by Fanduel, updated Oct 9, 1:33 AM ETBet at Fanduel
How has the line moved?
| Captured | 49ers spread | Total |
|---|---|---|
| Wed, Oct 7, 1:36 AM EDT | -2 | 44.5 |
| Wed, Oct 7, 11:12 AM EDT | -2.5 | 44 |
| Wed, Oct 7, 8:48 PM EDT | -2 | 44.5 |
| Thu, Oct 8, 6:24 AM EDT | -2 | 44.5 |
| Thu, Oct 8, 4:00 PM EDT | -2.5 | 44 |
| Fri, Oct 9, 1:36 AM EDT | -2.5 | 44 |
49ers spread
Total (over/under)
Eagles vs 49ers team comparison
| Eagles | 49ers | |
|---|---|---|
| 2-2 | Record | 4-0 |
| 18.8 | Points per game | 30.5 |
| 23.3 | Opponent points/game | 16.0 |
| -4.5 | Points differential | +14.5 |
| 0 | Head-to-head wins | 0 |
Injuries on both sides
| Team | Player | Pos | Status | Injury | Updated |
|---|---|---|---|---|---|
 Eagles | Jonathan Greenard | Linebacker | May play | Ankle | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Tucker Large | Safety | Out 4+ games | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Jakorian Bennett | Cornerback | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Grant Calcaterra | Tight End | Injury reserve | Back | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Andre' Sam | Safety | Injury reserve | Foot | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Eli Stowers | Tight End | Injury reserve | Quadriceps/hamstring | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Johnny Wilson | Wide Receiver | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Tanner McKee | Quarterback | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Elijah Moore | Wide Receiver | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Micah Morris | Guard | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Cole Payton | Quarterback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Marcus Epps | Safety | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Landon Dickerson | Guard | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Jalen Carter | Defensive Tackle | May play | Wrist | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Cooper DeJean | Cornerback | May play | Calf | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Andrew Mukuba | Safety | May play | Knee | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Saquon Barkley | Running Back | May play | Hamstring | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Dallas Goedert | Tight End | May play | Knee | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Tank Bigsby | Running Back | Injury reserve | Abdomen | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Will Shipley | Running Back | May play | Foot | Wed, Oct 7, 8:15 PM EDT |
| Eagles | DeVonta Smith | Wide Receiver | May play | Hamstring | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Hollywood Brown | Wide Receiver | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Fred Johnson | Offensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Eagles | AJ Epenesa | Defensive End | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Zack Baun | Linebacker | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Jihaad Campbell | Linebacker | May play | Campbell recorded nine solo ta… | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Jordan Davis | Defensive Tackle | May play | Calf | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Moro Ojomo | Defensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Lane Johnson | Offensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Quinyon Mitchell | Cornerback | May play | Knee | Wed, Oct 7, 8:15 PM EDT |
| Eagles | Drew Kendall | Center | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
 49ers | Isaac Guerendo | Running Back | Out 4+ games | Pectoral | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Brandon Aiyuk | Wide Receiver | Reserve | Head | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Christian Kirk | Wide Receiver | Injury reserve | Calf | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Mykel Williams | Defensive End | Out 4+ games | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Ricky Pearsall | Wide Receiver | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Andrew Farmer II | Defensive End | Injury reserve | Back | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Darrick Forrest | Safety | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Mikail Kamara | Defensive End | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Sam Okuayinonu | Defensive Tackle | Injury reserve | Foot | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Brett Toth | Center | Injury reserve | Concussion | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Nate Hobbs | Cornerback | Injury reserve | ir | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Nick Martin | Linebacker | Injury reserve | Hamstring | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Austen Pleasants | Offensive Tackle | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Nick Zakelj | Offensive Tackle | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Alfred Collins | Defensive Tackle | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Tatum Bethune | Linebacker | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Enrique Cruz Jr. | Offensive Tackle | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jordan James | Running Back | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Ephesians Prysock | Cornerback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Kurtis Rourke | Quarterback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jordan Watkins | Wide Receiver | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| 49ers | De'Zhaun Stribling | Wide Receiver | Injury reserve | Ankle | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jake Tonges | Tight End | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Kyle Juszczyk | Fullback | Out | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Khalid Kareem | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| 49ers | George Kittle | Tight End | May play | Achilles | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Eddy Pineiro | Place Kicker | May play | Illness | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Keion White | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Kaelon Black | Running Back | May play | Illness | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Romello Height | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jack Jones | Cornerback | May play | Foot | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Demarcus Robinson | Wide Receiver | Injury reserve | Ankle | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Mike Evans | Wide Receiver | May play | Ribs | Wed, Oct 7, 8:15 PM EDT |
| 49ers | James Thompson Jr. | Defensive Tackle | Likely out | doubtful | Wed, Oct 7, 8:15 PM EDT |
| 49ers | C.J. West | Defensive Tackle | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Nick Bosa | Defensive End | Likely out | doubtful | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Dre Greenlaw | Linebacker | May play | Quadriceps | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Gracen Halton | Defensive Tackle | May play | Ankle | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Trent Williams | Offensive Tackle | May play | Neck | Wed, Oct 7, 8:15 PM EDT |
| 49ers | KhaDarel Hodge | Wide Receiver | May play | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jaden Dugger | Linebacker | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Marques Sigle | Safety | Out | out | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Upton Stout | Cornerback | May play | Shoulder | Wed, Oct 7, 8:15 PM EDT |
Consensus Bets on this game
No consensus data yet for Eagles at 49ers. Check back closer to game time.
Frequently asked questions
Who is favoured in Eagles vs 49ers on Sunday, January 3?
San Francisco 49ers are favoured by 2.5 points (-2.5)
What is the spread for Eagles vs 49ers on Sunday, January 3?
49ers -2.5, Eagles +2.5. Opened at -2 for 49ers
What time is Eagles vs 49ers on Sunday, January 3?
Sunday, January 3, 2027 at 8:20 PM EST, Levi's Stadium, San Francisco, CA
What is Eagles vs 49ers head-to-head record?
Eagles 0, 49ers 0 in recent games