NFL · Week 11
Cardinals vs Chiefs Betting Odds – Week 11
Sunday, November 22, 2026 · 1:00 PM EST · Arrowhead Stadium, Kansas City, MO
Odds by Fanduel, updated Oct 9, 3:38 AM ET
Week 11
Sunday, November 22
1:00 PM EST
@ Arrowhead Stadium, Kansas City, MO
- Arizona Cardinals are favored by 1 points at -159, Sunday, November 22 at 1:00 PM EST
- Expected total is 44.5 points, unchanged from the opening 44.5
- Chiefs Wide Receiver Tyquan Thornton is Out
Cardinals vs Chiefs odds
Odds by Fanduel, updated Oct 9, 3:38 AM ETBet at Fanduel
How has the line moved?
| Captured | Chiefs spread | Total |
|---|---|---|
| Wed, Oct 7, 3:38 AM EDT | PK | 44.5 |
| Wed, Oct 7, 1:14 PM EDT | PK | 44.5 |
| Wed, Oct 7, 10:50 PM EDT | +0.5 | 44.5 |
| Thu, Oct 8, 8:26 AM EDT | +0.5 | 44.5 |
| Thu, Oct 8, 6:02 PM EDT | +1 | 44.5 |
| Fri, Oct 9, 3:38 AM EDT | +1 | 44.5 |
Chiefs spread
Total (over/under)
Cardinals vs Chiefs team comparison
| Cardinals | Chiefs | |
|---|---|---|
| 1-3 | Record | 4-0 |
| 21.8 | Points per game | 29.5 |
| 29.3 | Opponent points/game | 19.3 |
| -7.5 | Points differential | +10.3 |
| 0 | Head-to-head wins | 0 |
Injuries on both sides
| Team | Player | Pos | Status | Injury | Updated |
|---|---|---|---|---|---|
 Cardinals | James Conner | Running Back | Injury reserve | Foot | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Tip Reiman | Tight End | Out 4+ games | Ankle | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Joey Blount | Safety | Injury reserve | Neck | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Zachary Carter | Defensive Tackle | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Kaleb Proctor | Defensive Tackle | Injury reserve | ir | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Chase Bisontis | Guard | Injury reserve | ir | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Trey Benson | Running Back | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Jameson Geers | Tight End | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Dadrion Taylor-Demerson | Safety | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Isaiah Adams | Guard | May play | Ankle | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Garrett Williams | Cornerback | May play | Achilles | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Carson Beck | Quarterback | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Andrew Billings | Defensive Tackle | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Reggie Virgil | Wide Receiver | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Kitan Crawford | Safety | Injury reserve | Ankle | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Jack Gibbens | Linebacker | May play | Shoulder | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Roy Lopez | Defensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Max Melton | Cornerback | May play | Toe | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Isaac Seumalo | Guard | May play | Shoulder | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Cody Simon | Linebacker | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Josh Fryar | Offensive Tackle | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Will Johnson | Cornerback | Injury reserve | Neck | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Hjalte Froholdt | Center | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Walter Nolen III | Defensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Mack Wilson Sr. | Linebacker | May play | Thumb | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Josh Sweat | Linebacker | May play | Groin | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Cameron Robertson | Linebacker | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Starling Thomas V | Cornerback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Andrew Wingard | Safety | May play | Knee | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Hunter Long | Tight End | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Paris Johnson Jr. | Offensive Tackle | Injury reserve | Biceps | Wed, Oct 7, 8:15 PM EDT |
| Cardinals | Jeremiyah Love | Running Back | May play | Ankle | Wed, Oct 7, 8:15 PM EDT |
 Chiefs | Omarr Norman-Lott | Defensive Tackle | Out 4+ games | Knee | Wed, Oct 7, 8:15 PM EDT |
| Chiefs | Ethan Downs | Linebacker | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Chiefs | John Michael Gyllenborg | Tight End | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Chiefs | Jeff Caldwell | Wide Receiver | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Chiefs | Jimmy Holiday | Wide Receiver | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Chiefs | Josh Simmons | Offensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Chiefs | Matt Waletzko | Offensive Tackle | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Chiefs | Chamarri Conner | Safety | May play | Knee | Wed, Oct 7, 8:15 PM EDT |
| Chiefs | Bryson Eason | Defensive Tackle | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Chiefs | Garrett Nussmeier | Quarterback | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Chiefs | Diego Pounds | Offensive Tackle | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Chiefs | Jack Pyburn | Linebacker | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Chiefs | Jared Wiley | Tight End | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Chiefs | Mansoor Delane | Cornerback | May play | Shoulder | Wed, Oct 7, 8:15 PM EDT |
| Chiefs | Cooper McDonald | Linebacker | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Chiefs | Chris Jones | Defensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Chiefs | Felix Anudike-Uzomah | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Chiefs | L'Jarius Sneed | Cornerback | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Chiefs | Tyreke Smith | Defensive End | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Chiefs | Jadon Canady | Cornerback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Chiefs | Rashee Rice | Wide Receiver | May play | Hamstring | Wed, Oct 7, 8:15 PM EDT |
| Chiefs | Tyquan Thornton | Wide Receiver | Out | Ankle | Wed, Oct 7, 8:15 PM EDT |
Consensus Bets on this game
No consensus data yet for Cardinals at Chiefs. Check back closer to game time.
Frequently asked questions
Who is favoured in Cardinals vs Chiefs on Sunday, November 22?
Arizona Cardinals are favoured by 1 points (-1)
What is the spread for Cardinals vs Chiefs on Sunday, November 22?
Chiefs +1, Cardinals -1. Opened at PK for Chiefs
What time is Cardinals vs Chiefs on Sunday, November 22?
Sunday, November 22, 2026 at 1:00 PM EST, Arrowhead Stadium, Kansas City, MO
What is Cardinals vs Chiefs head-to-head record?
Cardinals 0, Chiefs 0 in recent games