NFL · Week 2
Dolphins vs 49ers Betting Odds – Week 2
Last game: Sunday, September 20, 2026 · 4:25 PM EDT · Levi's Stadium, San Francisco, CA
Odds by Fanduel, updated Oct 9, 1:32 AM ET
Week 2
Sunday, September 20
4:25 PM EDT
@ Levi's Stadium, San Francisco, CA
Final: Dolphins 13, 49ers 35
- Miami Dolphins are favored by 3.5 points at -471
- Expected total is 45 points, unchanged from the opening 45
- Dolphins Cornerback Reese Taylor is Out
Dolphins vs 49ers odds
Odds by Fanduel, updated Oct 9, 1:32 AM ETBet at Fanduel
How has the line moved?
| Captured | 49ers spread | Total |
|---|---|---|
| Mon, Sep 14, 4:25 PM EDT | +4.5 | 45 |
| Sat, Sep 19, 1:27 PM EDT | +4.5 | 45 |
| Thu, Sep 24, 10:30 AM EDT | +4 | 45 |
| Tue, Sep 29, 7:33 AM EDT | +4 | 45 |
| Sun, Oct 4, 4:35 AM EDT | +3.5 | 45 |
| Fri, Oct 9, 1:38 AM EDT | +3.5 | 45 |
49ers spread
Total (over/under)
Dolphins vs 49ers team comparison
| Dolphins | 49ers | |
|---|---|---|
| 0-4 | Record | 4-0 |
| 11.5 | Points per game | 30.5 |
| 25.3 | Opponent points/game | 16.0 |
| -13.8 | Points differential | +14.5 |
| 0 | Head-to-head wins | 1 |
Injuries on both sides
| Team | Player | Pos | Status | Injury | Updated |
|---|---|---|---|---|---|
 Dolphins | Darrell Baker Jr. | Cornerback | Out 4+ games | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | Storm Duck | Cornerback | Out 4+ games | Knee | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | Rene Konga | Defensive Tackle | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | Kenneth Grant | Defensive Tackle | Injury reserve | Toe | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | Trey Moore | Linebacker | Injury reserve | ir | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | Cole Turner | Tight End | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | DJ Campbell | Guard | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | Brady Cook | Quarterback | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | Chukwuebuka Godrick | Offensive Tackle | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | Justin Joly | Tight End | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | Reese Taylor | Cornerback | Out | Quadriceps | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | Jalen Tolbert | Wide Receiver | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | Kyle Louis | Linebacker | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | Ronnie Harrison Jr. | Linebacker | Injury reserve | Hamstring | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | Tucker Addington | Long Snapper | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | Chop Robinson | Linebacker | May play | Concussion | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | Seydou Traore | Tight End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | Marcellas Dial Jr. | Cornerback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | Robert Beal Jr. | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | Jaylen Wright | Running Back | May play | Foot | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | Caleb Douglas | Wide Receiver | May play | Ankle | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | Chris Bell | Wide Receiver | May play | Knee | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | JuJu Brents | Cornerback | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | Ryan Miller | Wide Receiver | May play | Hip | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | De'Von Achane | Running Back | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | Aaron Brewer | Center | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | Jackson Woodard | Linebacker | May play | Ankle | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | Dante Trader Jr. | Safety | May play | Knee | Wed, Oct 7, 8:15 PM EDT |
| Dolphins | Austin Jackson | Offensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
 49ers | Isaac Guerendo | Running Back | Out 4+ games | Pectoral | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Brandon Aiyuk | Wide Receiver | Reserve | Head | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Christian Kirk | Wide Receiver | Injury reserve | Calf | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Mykel Williams | Defensive End | Out 4+ games | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Ricky Pearsall | Wide Receiver | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Andrew Farmer II | Defensive End | Injury reserve | Back | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Darrick Forrest | Safety | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Mikail Kamara | Defensive End | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Sam Okuayinonu | Defensive Tackle | Injury reserve | Foot | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Brett Toth | Center | Injury reserve | Concussion | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Nate Hobbs | Cornerback | Injury reserve | ir | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Nick Martin | Linebacker | Injury reserve | Hamstring | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Austen Pleasants | Offensive Tackle | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Nick Zakelj | Offensive Tackle | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Alfred Collins | Defensive Tackle | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Tatum Bethune | Linebacker | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Enrique Cruz Jr. | Offensive Tackle | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jordan James | Running Back | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Ephesians Prysock | Cornerback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Kurtis Rourke | Quarterback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jordan Watkins | Wide Receiver | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| 49ers | De'Zhaun Stribling | Wide Receiver | Injury reserve | Ankle | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jake Tonges | Tight End | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Kyle Juszczyk | Fullback | Out | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Khalid Kareem | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| 49ers | George Kittle | Tight End | May play | Achilles | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Eddy Pineiro | Place Kicker | May play | Illness | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Keion White | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Kaelon Black | Running Back | May play | Illness | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Romello Height | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jack Jones | Cornerback | May play | Foot | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Demarcus Robinson | Wide Receiver | Injury reserve | Ankle | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Mike Evans | Wide Receiver | May play | Ribs | Wed, Oct 7, 8:15 PM EDT |
| 49ers | James Thompson Jr. | Defensive Tackle | Likely out | doubtful | Wed, Oct 7, 8:15 PM EDT |
| 49ers | C.J. West | Defensive Tackle | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Nick Bosa | Defensive End | Likely out | doubtful | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Dre Greenlaw | Linebacker | May play | Quadriceps | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Gracen Halton | Defensive Tackle | May play | Ankle | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Trent Williams | Offensive Tackle | May play | Neck | Wed, Oct 7, 8:15 PM EDT |
| 49ers | KhaDarel Hodge | Wide Receiver | May play | Knee | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Jaden Dugger | Linebacker | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Marques Sigle | Safety | Out | out | Wed, Oct 7, 8:15 PM EDT |
| 49ers | Upton Stout | Cornerback | May play | Shoulder | Wed, Oct 7, 8:15 PM EDT |
Consensus Bets on this game
No consensus data yet for Dolphins at 49ers. Check back closer to game time.
Previous games
Frequently asked questions
Who is favoured in Dolphins vs 49ers?
Miami Dolphins were favoured by 3.5 points (-3.5)
What is the spread for Dolphins vs 49ers?
49ers +3.5, Dolphins -3.5. Opened at +4.5 for 49ers
What time is Dolphins vs 49ers?
No game is currently scheduled
What is Dolphins vs 49ers head-to-head record?
Dolphins 0, 49ers 1 in recent games