NFL · Week 3
Panthers vs Browns Betting Odds – Week 3
Last game: Sunday, September 27, 2026 · 1:00 PM EDT · Huntington Bank Field, Cleveland, OH
Odds by Fanduel, updated Oct 9, 4:24 AM ET
Week 3
Sunday, September 27
1:00 PM EDT
@ Huntington Bank Field, Cleveland, OH
Final: Panthers 18, Browns 21
- Cleveland Browns are favored by 2.5 points at -288
- Expected total is 43 points, down from the opening 43.5
- Panthers Offensive Tackle Ikem Ekwonu is Out 4+ games
Panthers vs Browns odds
Odds by Fanduel, updated Oct 9, 4:24 AM ETBet at Fanduel
How has the line moved?
| Captured | Browns spread | Total |
|---|---|---|
| Mon, Sep 21, 1:00 PM EDT | -1.5 | 43.5 |
| Fri, Sep 25, 1:42 AM EDT | -1.5 | 43.5 |
| Mon, Sep 28, 2:24 PM EDT | -2 | 43 |
| Fri, Oct 2, 3:07 AM EDT | -2 | 43.5 |
| Mon, Oct 5, 3:49 PM EDT | -2 | 43 |
| Fri, Oct 9, 4:31 AM EDT | -2.5 | 43 |
Browns spread
Total (over/under)
Panthers vs Browns team comparison
| Panthers | Browns | |
|---|---|---|
| 2-2 | Record | 3-1 |
| 30.3 | Points per game | 20.3 |
| 27.3 | Opponent points/game | 23.8 |
| +3.0 | Points differential | -3.5 |
| 0 | Head-to-head wins | 1 |
Injuries on both sides
| Team | Player | Pos | Status | Injury | Updated |
|---|---|---|---|---|---|
 Panthers | Ikem Ekwonu | Offensive Tackle | Out 4+ games | Knee | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Taylor Moton | Offensive Tackle | Out 4+ games | Illness | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Tershawn Wharton | Defensive Tackle | Out 4+ games | Neck | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Nic Scourton | Linebacker | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Chris Brazzell II | Wide Receiver | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Brady Christensen | Guard | Injury reserve | Hamstring | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Trevor Etienne | Running Back | Injury reserve | Ankle | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Bam Martin-Scott | Linebacker | Injury reserve | Hamstring | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Patrick Jones II | Linebacker | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Cam Jackson | Defensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Haynes King | Quarterback | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Panthers | John Metchie III | Wide Receiver | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Albert Reese IV | Offensive Tackle | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Ja'Tavion Sanders | Tight End | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Zakee Wheatley | Safety | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Jalen Coker | Wide Receiver | May play | Quadriceps | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Bobby Brown III | Defensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Tyrel Dodson | Linebacker | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Chau Smith-Wade | Cornerback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Nick Scott | Safety | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Claudin Cherelus | Linebacker | Injury reserve | Shoulder | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Jonathon Brooks | Running Back | Injury reserve | Brooks is expected to undergo … | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Trevis Gipson | Linebacker | May play | Concussion | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Devin Lloyd | Linebacker | May play | Calf | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Jaelan Phillips | Linebacker | May play | Hamstring | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Xavier Legette | Wide Receiver | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Mike Jackson | Cornerback | Injury reserve | Groin | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Damien Lewis | Guard | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Jaycee Horn | Cornerback | Injury reserve | Quadriceps | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Monroe Freeling | Offensive Tackle | May play | Knee | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Princely Umanmielen | Linebacker | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Panthers | Lee Hunter | Defensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
 Browns | Jeremiah Owusu-Koramoah | Linebacker | Out 4+ games | out | Wed, Oct 7, 8:15 PM EDT |
| Browns | Parker Brailsford | Center | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Browns | Damarri Mathis | Cornerback | Injury reserve | Undisclosed | Wed, Oct 7, 8:15 PM EDT |
| Browns | Elijah Chatman | Defensive Tackle | Injury reserve | Quadriceps | Wed, Oct 7, 8:15 PM EDT |
| Browns | Kalia Davis | Defensive Tackle | Injury reserve | Quadriceps | Wed, Oct 7, 8:15 PM EDT |
| Browns | Dillon Gabriel | Quarterback | Injury reserve | Back | Wed, Oct 7, 8:15 PM EDT |
| Browns | Joe Royer | Tight End | Out 4+ games | Personal | Wed, Oct 7, 8:15 PM EDT |
| Browns | Edefuan Ulofoshio | Linebacker | Injury reserve | Biceps | Wed, Oct 7, 8:15 PM EDT |
| Browns | Alex Wright | Defensive End | Injury reserve | Achilles | Wed, Oct 7, 8:15 PM EDT |
| Browns | Teven Jenkins | Guard | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Browns | Taylen Green | Quarterback | Not playing | Coach's decision | Wed, Oct 7, 8:15 PM EDT |
| Browns | Noah Igbinoghene | Cornerback | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Browns | Justin Jefferson | Linebacker | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Browns | Toriano Pride Jr. | Cornerback | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Browns | Daniel Thomas | Safety | Not playing | inactive | Wed, Oct 7, 8:15 PM EDT |
| Browns | Dylan Sampson | Running Back | Injury reserve | Knee | Wed, Oct 7, 8:15 PM EDT |
| Browns | Maliek Collins | Defensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Browns | Elgton Jenkins | Center | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Browns | Dawand Jones | Offensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Browns | Tyson Campbell | Cornerback | May play | Knee | Wed, Oct 7, 8:15 PM EDT |
| Browns | Grant Delpit | Safety | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Browns | Mason Graham | Defensive Tackle | Likely out | doubtful | Wed, Oct 7, 8:15 PM EDT |
| Browns | Tytus Howard | Offensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Browns | Quincy Williams | Linebacker | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Browns | Tylan Wallace | Wide Receiver | May play | Knee | Wed, Oct 7, 8:15 PM EDT |
| Browns | Derek Barnett | Defensive End | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
| Browns | Mike Hall Jr. | Defensive Tackle | May play | questionable | Wed, Oct 7, 8:15 PM EDT |
Consensus Bets on this game
No consensus data yet for Panthers at Browns. Check back closer to game time.
Previous games
Frequently asked questions
Who is favoured in Panthers vs Browns?
Cleveland Browns were favoured by 2.5 points (-2.5)
What is the spread for Panthers vs Browns?
Browns -2.5, Panthers +2.5. Opened at -1.5 for Browns
What time is Panthers vs Browns?
No game is currently scheduled
What is Panthers vs Browns head-to-head record?
Panthers 0, Browns 1 in recent games